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Mediso - nanoScan Family

nanoScan Family: the next generation in vivo preclinical imaging platform

The nanoScan Family combines the industry’s highest performing PET and SPECT technology with robust and cutting-edge CT and MR. These nine combinations include standalone, bi-mode, and tri-mode systems to address the unique imaging needs and requirements of your institute. Easy upgradeability and a continuous pipeline of nanoScan innovations keeps your system at the forefront of preclinical imaging.

The high-end subsystem combinations are integrated through a precision-aligned gantry, universal software interface, and common animal handling solutions.

SPECT
- 275 µm visible resolution
- over 97%
quantification accuracy
- up to 10,000 cps/MBq
sensitivity by 100 pinholes

 

MRI 3T and 1T
- 100 µm resolution
- low fringe fields
 - can be installed almost anywhere

 

PET
- 700 µm visible resolution
- over 97% quantification
accuracy
- 9% maximal sensitivity

 

CT
- 30 µm resolution
- 80 W X-ray power
- ultra low dose acquisition protocol

Expending your capabilities for life science research and drug development

Key research areas: Cancer Biology, Inflammatory Disease/Autoimmune, Neurobiology/CNS/Neurodegeneration, Cardiology or Vascular Biology, Diabetes, Liver Disease, Lung Disease, Urology, and many more...

Select applications: Monitoring Treatment Response, Pharmacokinetics, Pharmacodynamics, ADME, Metabolic Studies, Gene Expression, Protein Expression, Receptor Binding, Toxicology, Cell Tracking and Disease Model Development.

Exclusive Features of the nanoScan Family:

    • Highest visible resolution: SPECT-300 um, PET-700 um
    • Best PET and SPECT quantification accuracy: over 97%
    • Universal MultiCell™ Small Animal Support and Monitoring System
    • Mouse, rat, multi-mouse, marmoset, rabbit, and monkey imaging support
    • Intuitive, powerful acquisition and post-processing workstations
    • Exclusive GPU-based Teraflop speed 3D Tera-Tomo™ Reconstruction Engine
    • Cardiac and Respiratory gating
    • PET and SPECT list mode (energy, time, location) acquisition
    • Affordable 1T and translational 3T MRI offerings
    • Flexible PET and SPECT offerings to fit every budget and application
    • Factory supported equipment lifetime guarantee (>10 years)

Common nanoScan Components

Mediso maximizes common elements on the nanoScan platform to enhance the user experience and reduce the learning curve to full system utilization. In addition, these common components have a positive impact on workflow, throughput, and reliability.

    1. MultiCell Small Animal Handling System
      • Easily dock imaging chambers to gantry with a single quick-release button
      • Dockable services include animal ECG, respiration, and temperature monitoring
      • Dockable anesthesia delivery/scavenging and closed-circuit bed heating
      • All imaging chambers fully compatible with PET/SPECT/CT/MR
      • Pathogen-free sterile environment for immuno-compromised animals
      • Widest range of animals are supported:
      • MultiCell Anaesthesia connection with nose coneWidest range of animals are supported:
        • Mouse, multi-mouse “hotels”
        • Rat large and extra large
        • Marmoset
        • Rabbit
        • Monkey
    2. Physiological Monitoring Package (Respiratory/ECG/Temperature)
      • Nucline Acqusition Software: CT Scout View with ECG gatingRespiratory, ECG and temperature signals of the animal are registered real-time to monitor the physiological status of the animal during the scan
      • Monitor physiology from the operator console or from the gantry-mounted touch screen monitor
      • ECG monitoring module: 3 ECG electrodes, variable gain, 1200 bpm max, ECG waveform and trend display
      • Respiration monitoring module: Pneumatic pillow, Respiration waveform display
      • Temperature monitoring module: rectal probe for continuous monitoring
    3. Physiological Gating Packages (optional)
      • ECG trigger module
      • Respiratory trigger module
      • Additional gating signals available
    4. Nucline in persistent scope modeNucline™ All-modality Acquisition Software
      • Common planning and acquisition platform for all imaging modalities PET/SPECT/CT/MR
      • Developed from Mediso clinical imaging devices and optimized for preclinical imaging
      • Common interface integrates a wide range of functionalities including planning, acquisition, calibration, data management, reconstruction, and visualization
      • Adheres to common industry standards and provides DICOM images stored on the included DICOM server
    5. Tera-Tomo™ 3D SPECT and PET reconstruction engine
      • PET and SPECT resolution close to the physical limits
      • Reconstruction and acquisition can occur in parallel
      • Concurrent on-the-fly reconstruction and post reconstruction
      • Advanced graphical processing unit (GPU) with teraflop speed
      • Corrections for physical factors such as detector geometry, continuous Monte Carlo DOI estimation, object attenuation, scatter, randoms, and dead time
      • Quantitative 3D SPECT and PET reconstruction developed in collaboration with academic partners
    6. Interview™ FUSION post processing and analysis software

    7. VivoQuant post-processing analysis and viewing software by inviCRO-a Konica Minolta company

    8. DICOM Server Software.